TRIMming TGF-β signals in Th17 cells
- Resource Type
- Article
- Authors
- Rapaport, Aaron S.; Ouyang, Wenjun
- Source
- The Journal of Experimental Medicine; July 2018, Vol. 215 Issue: 7 p1775-1776, 2p
- Subject
- Language
- ISSN
- 00221007; 15409538
The precise downstream mediators of TGF-β signaling in Th17 and T reg cells remain unclear. In this issue of JEM, Tanaka et al. report that Trim33 transduces TGF-β signals in Th17 cells to generate an optimal proinflammatory cytokine profile.