A mouse includes a main body and a control circuit. A left button, a number of pressure sensors, a right button, and a control button are positioned on the main body. The control circuit includes a control unit, an acceleration sensor, and a wireless transmitter. The left button, the pressure sensors, the right button, the control button, the acceleration sensor, and the wireless transmitter are connected to the control unit. When the mouse is placed in the mouth of a user, the left button, the pressure sensors, and the right button are operated by the tongue of the user. The control button is bitten by the teeth of the user, to turn on the acceleration sensor. The acceleration sensor senses movement of the head of the user, and cooperates with the control unit and the wireless transmitter to control a cursor of a computer to move.