According to the Pseudo-random numbers for the end-hopping technique, an end-hopping communication model combined with Stream Cipher is established, then the key problems of the model are discussed. The model shows the communication based on the clocked nonlinear sequence use random hopping port, which could prevent hackers from seizing the hopping rules of port, and it is an effective way to secure the information. The work analyzes the security of the model , verifies the feasibility of the communications technology in theory, and the performance of the program is simulated.