High Throughput Cell Mechanophenotyping via Microfluidic Constrictions with Multiplexed Electrical Sensors
- Resource Type
- Conference
- Authors
- Asmare, Norh; Arifuzzman, A K M; Wang, Ningquan; Boya, Mert; Liu, Ruxiu; Sarioglu, A. Fatih
- Source
- 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII) Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII), 2019 20th International Conference on. :948-951 Jun, 2019
- Subject
- Bioengineering
Components, Circuits, Devices and Systems
Fields, Waves and Electromagnetics
Photonics and Electrooptics
Power, Energy and Industry Applications
Robotics and Control Systems
Computer architecture
Microprocessors
Sensors
Throughput
Microfluidics
Strain
Electrodes
Lab-On-A-Chip
Microfluidic
mechanophenotyping
constriction
deformability cytometry
- Language
- ISSN
- 2167-0021
The work presented herein shows a microfluidic cytometry platform that uses constrictive channels monitored with a multiplexed electrical sensing network to measure cell mechanical properties. The parallel microfluidic architecture combined with code division multiplexed electrical sensing of cells enable throughput levels that are otherwise not possible in constriction transit time measurement-based devices.