Diagnosis abnormal cervical tissue by elastic light scattering spectroscopy and correlation with the results of Pap-smear examination
- Resource Type
- Conference
- Authors
- Canpolat, Murat; Denkceken, Tuba; Karaveli, Seyda; Pestereli, Elif; Erdogan, Gulgun; Ozel, Deniz; Bilge, Ugur; Simsek, Tayup
- Source
- 2010 15th National Biomedical Engineering Meeting Biomedical Engineering Meeting (BIYOMUT), 2010 15th National. :1-4 Apr, 2010
- Subject
- Bioengineering
Communication, Networking and Broadcast Technologies
Computing and Processing
General Topics for Engineers
Robotics and Control Systems
Light scattering
Spectroscopy
Watermarking
Robustness
Discrete cosine transforms
Fuzzy neural networks
Copyright protection
Humans
Frequency domain analysis
Digital images
- Language
We have investigated the potential application of elastic light single-scattering spectroscopy in detection of cervical precancerous lesions non-invasively and in real time. Ex-vivo spectroscopic measurements were performed on 95 cervix biopsy tissue of 60 patients. Normal cervix tissue from 10 patients after hysterectomy was used as a control group. It was found that the spectral slope was positive and negative for the spectra taken on normal cervix and precancerous cervix tissue respectively. Sign of the spectral slopes were used as a parameter to differentiate normal cervix tissue from dysplastic cervix tissue. Elastic light single-scattering spectroscopy measurements in defining cervical tissue were 100% consistent with Pap-smear results.