Preparation and Blood Compatibility of Oxidized-chitosan Films
- Resource Type
- Academic Journal
- Authors
- Yue Dong YANG; Jiu Gao YU; Yong Guo ZHOU; Pei Guo LI
- Source
- 中国化学快报(英文版) / CHINESE CHEMICAL LETTERS. 16(7):991-994
- Subject
- Chitosan
blood compatibility
modified chitosan membrane
nitrogen dioxide
- Language
- Chinese
- ISSN
- 1001-8417
Chitosan membrane was modified by the selective oxidization of chitosan molecules on its surface with NO2 gas. FTIR spectra indicated there were plenty of-COOH and -COO- groups on the modified membrane surface. The SEM study showed the modified membrane surface was rough rather than smooth as chitosan membrane. All antithrombosis test, hemolysis test and blood cell morphology observation with SEM revealed that modified chitosan membranes have superior blood compatibility to chitosan.