Uniform microdroplets and designed microparticles generated by a microfluidic device with solvent evaporation are proved to have a significant impact on our everyday life such as recently in cosmetics, medicine, production of clean energy, reduction in energy consumption, the ultra-small magnets and sensors, and so on. Moreover, the properties of materials generated by monodispersed microdroplets from microfluidic devices are incredibly dependent on the synthesis method, especially on the processing route. However, all conventional microfluidic devices such like Tjunction single nozzle device and the glass capillary devices can only work in a researching scale. Then, a question raised, which is, how to increase productivity on the micro level by microfluidic devices to satisfy manufacture but without sacrificing their inherent advantages especially the low cost and the monodispersity. To solve this problem, a lot of compact design based on different microfluidic mechanism have been launched. Microchannel Emulsification and SPG (Shirasu Porous Glass) membrane are tow of them and provide competitive characteristics on this purpose. Regarding Microchannel Emulsification, in this thesis, the feasibility of generating uniform drug-loaded(sirolimus) PLGA biodegradable microparticles have been tested using both grooved and straight-through microchips to optimise the productivity while keeping good level in monodispersity. The results from both of two different types of chips show perfect uniform microparticles to fit the design which were expected prior to the practical experiments. The formulas based on the different types of devices were explored and determined by the morphology of the resultant microparticles and the uniformity of the emulsion. Besides, the possibility of long term producing of the microchip was verified which indicated an alternative meathod to scale up the productivity by grooved microchannel device. A relevant drug release profile was then worked out to demonstrate the controllable drug release by encapsulation of sirolimus in uniform PLGA ( Poly(lactide-co-glycolide)) microsperes. Two types of SPG membrane were utilised in the research with cylindracal shape and average pore size of 10µm and 30µm respectively. W/O ( water in oil) emulsion was generated successfully by SPG membrane with competitive productivity compare to both microchannel emulsification method and glass capillary device. The uniformity of the emulsion were observed at high level with low coefficient variation under 10%. The resultant silica particles from solidification of emulsion were detected with tunable size and porosity. The average size of both droplets and particles produced by SPG membrane are dominated by the average pore size of the membrane, the transmembrane pressure and the practical formula. It's worth to note, the whole strategy can be easy to scale-up by increasing the size of the membrane ( both in length and diameter). Finally, an distinguished W/O emulsion was generated successfully by both SPG membrane and grooved microchannel emulsification for biology applications. In this section, pre-designed Giant Vehicles were produced by the microfluidic device and indicated the remarkably monodispersed Giant Vehicles can be generated by both MCE( microchannel emulsification) and SPG membrane.