We describe the RF Quantum Upconverter (RQU) and describe its application to quantum metrology of electromagnetic modes between dc and the Very High Frequency band (VHF) ($\lesssim$300MHz). The RQU uses a Josephson interferometer made up of superconducting loops and Josephson junctions to implement a parametric interaction between a low-frequency electromagnetic mode (between dc and VHF) and a mode in the microwave C Band ($\sim$ 5GHz), analogous to the radiation pressure interaction between electromagnetic and mechanical modes in cavity optomechanics. The RQU can operate as a quantum-limited op-amp, or use protocols from optomechanics to implement non-classical measurement protocols equivalent to those used in cavity optomechanics, including back-action evading (BAE) measurements, sideband cooling, and two-mode squeezing. These protocols enable experiments using dc-VHF electromagnetic modes as quantum sensors.