A simplified decision rule to rule out deep vein thrombosis using clinical assessment and D‐dimer
- Resource Type
- Authors
- Roger E. G. Schutgens; Toshihiko Takada; Clive Kearon; Kerstin de Wit; Geert-Jan Geersing; Sameer Parpia; Johan Elf; Keying Xu
- Source
- Journal of Thrombosis and Haemostasis. 19:1752-1758
- Subject
- medicine.medical_specialty
Deep vein
030204 cardiovascular system & hematology
Fibrin Fibrinogen Degradation Products
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Internal medicine
D-dimer
medicine
Humans
In patient
Prospective Studies
cardiovascular diseases
Ultrasonography
Venous Thrombosis
business.industry
Hematology
Patient data
Decision rule
medicine.disease
Thrombosis
Confidence interval
Pre- and post-test probability
medicine.anatomical_structure
business
- Language
- ISSN
- 1538-7836
Background: Current clinical decision rules to exclude deep vein thrombosis (DVT) are underused partly because of their complexity. A simplified rule that can be easily applied would be more appealing to use in clinical practice. Methods: We used individual patient data from prospective diagnostic studies of patients suspected of DVT to develop a new clinical decision rule. The primary outcome was presence of DVT either at initial testing or during follow-up. DVT was considered safely excluded if the upper 95% confidence interval (CI) of DVT prevalence was