Resectoscopic treatment of atypical endometrial polyps in fertile women
- Resource Type
- Authors
- Uri Wiesenfeld; Luca Ronfani; Federica Scrimin; Secondo Guaschino; Stefania Inglese; Alberto Candiotto
- Source
- American journal of obstetrics and gynecology. 199(4)
- Subject
- Adult
medicine.medical_specialty
medicine.drug_class
Hysteroscopy
Levonorgestrel
Intrauterine device
Endometrium
Hysteroscopic resection
law.invention
Polyps
Randomized controlled trial
law
Endometrial Polyp
Atypia
Electrocoagulation
Medicine
atypical endometrial polyp
fertile women
hysteroscopic resection
Humans
neoplasms
Gynecology
medicine.diagnostic_test
business.industry
Obstetrics and Gynecology
Middle Aged
medicine.disease
Prognosis
digestive system diseases
medicine.anatomical_structure
Endometrial Hyperplasia
Female
business
Progestin
- Language
- ISSN
- 1097-6868
Objective The purpose of this study was to evaluate the long-term efficacy and prognosis of hysteroscopic resection and coagulation of the base of endometrial polyps with focal atypia in fertile women with or without progestin suppression. Study Design We conducted a quasi-randomized trial in which conservative treatment was offered to 21 patients who had endometrial polyps with focal atypia and a surrounding normal endometrium. The polyps were analyzed separately from their bases. Random biopsy specimens were taken from 4 standard places of the endometrium. Results Eighteen women (10 women with an intrauterine device and 8 women with no intrauterine device) completed the follow-up procedure. After 5 years, we found no difference in the 2 groups regarding recurrence of atypical polyps. Conclusion Conservative resectoscopic treatment may be considered in fertile women with atypical polyps if polyp base and surrounding endometrium are benign. If women want to become pregnant at short term, the use of progestins can be delayed, with a strict follow-up procedure. Larger studies should be encouraged.