Comparative study of codon usage profiles of Zingiber officinale and its associated fungal pathogens
- Resource Type
- Authors
- Ravail Singh; S. K. Gupta
- Source
- Molecular Genetics and Genomics. 296:1121-1134
- Subject
- 0106 biological sciences
0301 basic medicine
Genetics
Natural selection
biology
Host (biology)
food and beverages
Aspergillus flavus
General Medicine
biology.organism_classification
01 natural sciences
Genome
03 medical and health sciences
030104 developmental biology
Codon usage bias
Fusarium oxysporum
Zingiber officinale
Molecular Biology
Pathogen
010606 plant biology & botany
- Language
- ISSN
- 1617-4623
1617-4615
Codon usage bias influences the genetic features prevalent in genomes of all the organisms. It also plays a crucial role in establishing the host-pathogen relationship. The present study elucidates the role of codon usage pattern regarding the predilection of fungal pathogens Aspergillus flavus, Aspergillus niger, Fusarium oxysporum and Colletotrichum gloeosporioides towards host plant Zingiber officinale. We found a similar trend of codon usage pattern operative in plant and fungal pathogens. This concurrence might be attributed for the colonization of fungal pathogens in Z. officinale. The transcriptome of both plant and pathogens showed bias towards GC-ending codons. Natural selection and mutational pressure seem to be accountable for shaping the codon usage pattern of host and pathogen. We also identified some distinctive preferred codons in A. flavus, F. oxysporum and Z. officinale that could be regarded as signature codons for the identification of these organisms. Knowledge of favored, avoided and unique codons will help to devise strategies for reducing spice losses due to fungal pathogens.