[Untitled]
- Resource Type
- Authors
- Mervyn Singer; Jody Aberdein
- Source
- Critical Care. 10:203
- Subject
- medicine.medical_specialty
Septic shock
business.industry
MEDLINE
Placebo-controlled study
Critical Care and Intensive Care Medicine
medicine.disease
law.invention
Randomized controlled trial
law
Bronchiolitis
Current strength
medicine
Corticosteroid use
Paranoia
medicine.symptom
Intensive care medicine
business
- Language
- ISSN
- 1364-8535
Traditional teaching suggests that corticosteroids should be avoided during acute infectious episodes for fear of compromising the immune response. However, the outcome benefit shown through steroid administration in early septic shock implies this paranoia may be misplaced. We therefore performed a systematic review of the literature to identify the current strength of evidence for the use of corticosteroids in specified infections, and to make appropriate graded recommendations.