Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer
Resource Type
Article
Authors
Sharma, Shikhar ; Chung, Chi-Yeh ; Uryu, Sean ; Petrovic, Jelena ; Cao, Joan ; Rickard, Amanda ; Nady, Nataliya ; Greasley, Samantha ; Johnson, Eric ; Brodsky, Oleg ; Khan, Showkhin ; Wang, Hui ; Wang, Zhenxiong ; Zhang, Yong ; Tsaparikos, Konstantinos ; Chen, Lei ; Mazurek, Anthony ; Lapek, John ; Kung, Pei-Pei ; Sutton, Scott ; Richardson, Paul F. ; Greenwald, Eric C. ; Yamazaki, Shinji ; Jones, Rhys ; Maegley, Karen A. ; Bingham, Patrick ; Lam, Hieu ; Stupple, Alexandra E. ; Kamal, Aileen ; Chueh, Anderly ; Cuzzupe, Anthony ; Morrow, Benjamin J. ; Ren, Bin ; Carrasco-Pozo, Catalina ; Tan, Chin Wee ; Bhuva, Dharmesh D. ; Allan, Elizabeth ; Surgenor, Elliot ; Vaillant, François ; Pehlivanoglu, Havva ; Falk, Hendrik ; Whittle, James R. ; Newman, Janet ; Cursons, Joseph ; Doherty, Judy P. ; White, Karen L. ; MacPherson, Laura ; Devlin, Mark ; Dennis, Matthew L. ; Hattarki, Meghan K. ; De Silva, Melanie ; Camerino, Michelle A. ; Butler, Miriam S. ; Dolezal, Olan ; Pilling, Patricia ; Foitzik, Richard ; Stupple, Paul A. ; Lagiakos, H. Rachel ; Walker, Scott R. ; Hediyeh-Zadeh, Soroor ; Nuttall, Stewart ; Spall, Sukhdeep K. ; Charman, Susan A. ; Connor, Theresa ; Peat, Thomas S. ; Avery, Vicky M. ; Bozikis, Ylva E. ; Yang, Yuqing ; Zhang, Ming ; Monahan, Brendon J. ; Voss, Anne K. ; Thomas, Tim ; Street, Ian P. ; Dawson, Sarah-Jane ; Dawson, Mark A. ; Lindeman, Geoffrey J. ; Davis, Melissa J. ; Visvader, Jane E. ; Paul, Thomas A.
Source
In Cell Chemical Biology 19 October 2023 30(10):1191-1210
Subject
Language
ISSN
2451-9456