Phthalide derivative CD21 ameliorates ischemic brain injury in a mouse model of global cerebral ischemia: involvement of inhibition of NLRP3
- Resource Type
- ACADEMIC JOURNAL
- Li, Xin a; Shi, Meng-Qi a; Chen, Chu b; Du, Jun-Rong a, ⁎
- In International Immunopharmacology September 2020 86
Highlights •CD21 has a dose-dependent neuroprotective effect on ischemic brain injury.•CD21 can inhibit TLR4/NF-κB signaling pathway activation in 2VO mice.•CD21 can inhibit NLRP3/ASC/Caspase-1 signaling pathway activation in 2VO mice.