Association between hyponatremia, inflammation, and mortality in patients undergoing peritoneal dialysis: A nationwide observations.
- Resource Type
- Academic Journal
- Authors
- Erdogan B; Department of Nephrology, Gulhane Training and Research Hospital, University of Health Sciences, Ankara, Turkey.; Ata N; Republic of Turkey Ministry of Health, Ankara, Turkey.; Caglayan M; Department of Medical Biochemistry, Etlik City Hospital, Ankara, Turkey.; Gözükara MG; Department of Public Health, Ankara Yıldırım Beyazıt University-Faculty of Medicine, Ankara, Turkey.; Gemcioglu E; Department of Internal Medicine, Ankara Etlik City Hospital, Ankara, Turkey.; Sokmen FC; Department of Internal Medicine, Gulhane Training and Research Hospital, University of Health Sciences, Ankara, Turkey.; Yilmaz N; Department of Internal Medicine, Ankara City Hospital, Cankaya, Turkey.; Celik O; Republic of Turkey Ministry of Health, Ankara, Turkey.; Ayvali MO; Republic of Turkey Ministry of Health, Ankara, Turkey.; Ulgu MM; Republic of Turkey Ministry of Health, Ankara, Turkey.; Birinci S; Republic of Turkey Ministry of Health, Ankara, Turkey.
- Source
- Publisher: Blackwell Pub Country of Publication: Australia NLM ID: 101181252 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-9987 (Electronic) Linking ISSN: 17449979 NLM ISO Abbreviation: Ther Apher Dial Subsets: MEDLINE
- Subject
- Language
- English
Introduction: Hyponatremia is the most common electrolyte disorder often present in peritoneal dialysis (PD) patients. The aim of this retrospective study was to investigate the effect of hyponatremia on mortality in patients undergoing PD.
Methods: The health records of adult individuals with an inserted PD catheter identified via the centralized national e-health database were used.
Results: The mean age of the 846 patients included in the study was 52.48 years (±14.6). The mean sodium level was 136.51 mEq/L. Sodium levels <137 mEq/L were associated with higher death risk independent of comorbidities. There was a 0.821 times less reduction in mortality for each mEq /L increase in serum sodium.
Conclusion: Our study provides evidence that monitoring and adjusting serum sodium levels is crucial in managing PD patients with hyponatremia, as low serum sodium level was found to be a significant and independent predictor of mortality.
(© 2023 International Society for Apheresis and Japanese Society for Apheresis.)