This article discusses a retrospective case series conducted in China on lipodystrophia centrifugalis abdominalis infantilis (LCAI), a localized atrophic disease. The study analyzed the clinicopathological characteristics, treatment outcomes, and prognosis of 127 patients with LCAI. The patients were divided into two groups based on the stage of their condition. Treatment options included topical agents, hydroxychloroquine, and glucocorticoids. The study found that hydroxychloroquine or glucocorticoids were more effective than topical agents in treating LCAI. The maximum follow-up period was 17 years, and some patients showed complete recovery or partial improvement. The study also noted a possible relationship between LCAI and lupus erythematosus panniculitis. This research provides valuable insights into the treatment and management of LCAI. [Extracted from the article]