Decoding the morphofunctionality of the skin: The compelling need to rethink keratinocyte oncogenesis.
- Resource Type
- Article
- Authors
- Fernandez‐Figueras, Maria‐Teresa
- Source
- Journal of the European Academy of Dermatology & Venereology. Nov2023, Vol. 37 Issue 11, p2163-2164. 2p.
- Subject
- *KERATINOCYTES
*SKIN cancer
*ACTINIC keratosis
*CARCINOGENESIS
*CELL morphology
*CELL populations
- Language
- ISSN
- 0926-9959
Single-cell RNA-seq reveals actinic keratosis-specific keratinocyte subgroups and their crosstalk with secretory-papillary fibroblasts. Compared to normal skin, AK presented a larger number of mesenchymal fibroblasts and secretory-papillary fibroblasts, with the latter showing potential relevance in keratinocyte oncogenesis. [Extracted from the article]