2017; 66: 678 - 85. 3 Iijima S, Matunaga K. A case of allergic contact dermatitis caused by Olanedine solution-a diagnostic patch-testing method involving dried filter paper. Dear Editor, Olanexidine gluconate (Olanedine®, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan) is a relatively new biguanide antiseptic solution released in 2015 and now available in Japan. The histopathology of erythema on her thigh revealed acanthosis and dyskeratosis, with mild spongiosis, along with perivascular lymphocytic infiltrates in the dermis (Figure 2a,b). [Extracted from the article]