To model growth over time, statistical techniques are available in both structural equation modeling (SEM) and random effects modeling frameworks. Liu et al. proposed a transformation and an inverse transformation for the linear–linear piecewise growth model with an unknown random knot, an intrinsically nonlinear function, in the SEM framework. This method allowed for the incorporation of time-invariant covariates. While the proposed method made novel contributions in this area of research, the use of transformations introduces some challenges to model estimation and dissemination. This commentary aims to illustrate the significant contributions of the authors' proposed method in the SEM framework, along with presenting the challenges involved in implementing this method and opportunities available in an alternative framework. [ABSTRACT FROM AUTHOR]