Iron-Mediated Radical Nitrohalogenation Reactions of Enynes with tert -Butyl Nitrite.
- Resource Type
- Article
- Authors
- Ren, Yingming; Ge, Yaxin; Yan, Qinqin; Tian, Yunfei; Wu, Jilai; Yang, Yujie; Li, Lijun; Li, Zejiang
- Source
- Synlett. 2021, Vol. 32 Issue 12, p1192-1196. 5p.
- Subject
- *ENYNES
*NITRITES
*ORGANIC compounds
*GROUP 15 elements
*RING formation (Chemistry)
- Language
- ISSN
- 0936-5214
A radical nitrohalogenation/cyclization of various enynes with tert -butyl nitrite has been developed that conveniently introduces useful nitro and halo groups into organic compounds. Some control experiments were performed to elucidate the mechanism. Further functional transformations proceeded well in this reaction system. [ABSTRACT FROM AUTHOR]