The NEMP family supports metazoan fertility and nuclear envelope stiffness.
- Resource Type
- Article
- Authors
- Yonit Tsatskis; Rosenfeld, Robyn; Pearson, Joel D.; Boswell, Curtis; Yi Qu; Kyunga Kim; Fabian, Lacramioara; Mohammad, Ariz; Xian Wang; Robson, Michael I.; Krchma, Karen; Jun Wu; Gonçalves, João; Hodzic, Didier; Shu Wu; Potter, Daniel; Pelletier, Laurence; Dunham, Wade H.; Gingras, Anne-Claude; Yu Sun
- Source
- Science Advances. 8/26/2020, Vol. 6 Issue 35, p1-12. 12p.
- Subject
- *NUCLEAR membranes
*MEIOSIS
*GERMINAL vesicles
*STEM cell niches
*FERTILITY
*LYSIS
*DEVELOPMENTAL biology
- Language
- ISSN
- 2375-2548
The article offers information on nuclear envelope membrane protein 1 (NEMP) family supports metazoan fertility and nuclear envelope stiffness. It mentions multi-transmembrane nuclear envelope (NE) protein with homologs found in all metazoans; No genetic models exist for Nemp function in any system; and Super-resolution microscopy revealed that dNemp localizes to inner nuclear membranes (INMs).