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1 . Academic Journal
Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury
저자
by
Jan Lj. Miljkovic
;
Nils Burger
;
Justyna M. Gawel
;
John F. Mulvey
;
Abigail A.I. Norman
, et al.
소스
Redox Biology, Vol 55, Iss , Pp 102429- (2022)
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7 . Academic Journal
GPR40 full agonism exerts feeding suppression and weight loss through afferent vagal nerve.
저자
by
Hikaru Ueno
;
Ryo Ito
;
Shin-Ichi Abe
;
Hitomi Ogino
;
Minoru Maruyama
, et al.
소스
PLoS ONE, Vol 14, Iss 9, p e0222653 (2019)
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7 . Academic Journal
Discovery and development of a selective GPR40/FFAR1 agonist, fasiglifam, for treatment of type 2 diabetes mellitus / 『GPR40/FFAR1 アゴニストの薬理作用』 新規糖尿病治療薬 GPR40/FFAR1 選択的アゴニスト Fasiglifamの研究開発
저자
by
Yoshiyuki Tsujihata
;
辻畑 善行
.
소스
日本薬理学雑誌 / Folia Pharmacologica Japonica. 2014, 144(2):59
Scopus
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4 . Academic Journal
A novel antidiabetic drug, fasiglifam/TAK-875, acts as an ago-allosteric modulator of FFAR1.
저자
by
Chiori Yabuki
;
Hidetoshi Komatsu
;
Yoshiyuki Tsujihata
;
Risa Maeda
;
Ryo Ito
, et al.
소스
PLoS ONE, Vol 8, Iss 10, p e76280 (2013)
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7 .
Discovery of a novel series of indolinylpyrimidine-based GPR119 agonists: Elimination of ether-a-go-go-related gene liability using a hydrogen bond acceptor-focused approach
저자
by
Yoshiyuki Tsujihata
;
Hirohisa Miyashita
;
Kae Matsuda
;
Masahiro Kamaura
;
Shin-ichi Abe
, et al.
소스
Bioorganicmedicinal chemistry
. 34
Open Access (OpenAIRE)
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7 .
Discovery of a novel series of GPR119 agonists: Design, synthesis, and biological evaluation of N-(Piperidin-4-yl)-N-(trifluoromethyl)pyrimidin-4-amine derivatives
저자
by
Tomoyuki Kitazaki
;
Kae Matsuda
;
Hirohisa Miyashita
;
Shinji Iwasaki
;
Kenjiro Sato
, et al.
소스
Bioorganic & Medicinal Chemistry
. 41:116208
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7 .
Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia
저자
by
Yoshiyuki Tsujihata
;
Tomoko Satomi
;
Satoshi Yamamoto
;
Kazumasa Miyamoto
;
Hiromitsu Fuse
, et al.
소스
EBioMedicine, Vol 24, Iss C, Pp 147-158 (2017)
EBioMedicine
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7 . Academic Journal
Design, Synthesis, and Biological Activity of Potent and Orally Available G Protein-Coupled Receptor 40 Agonists.
저자
by
Shinobu Sasaki
;
Shuji Kitamura
;
Nobuyuki Negoro
;
Masami Suzuki
;
Yoshiyuki Tsujihata
, et al.
소스
Journal of Medicinal Chemistry
. Mar2011, Vol. 54 Issue 5, p1365-1378. 14p.
Full Text (ACS)
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7 .
1161-P: SCO-267, a GPR40 Full Agonist, Improves Glycemic and Body Weight Control More Than That by Fasiglifam in Rat Models of Diabetes and Obesity
저자
by
Mitsugi Ookawara
;
Koji Takeuchi
;
Yusuke Moritoh
;
Hitomi Ogino
;
Tomoki Yoshihara
, et al.
소스
Diabetes
. 68
Scopus
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7 .
GPR40 full agonism exerts feeding suppression and weight loss through afferent vagal nerve
저자
by
Nobuhiro Nishigaki
;
Hikaru Ueno
;
Yasufumi Miyamoto
;
Hirohisa Miyashita
;
Koji Takeuchi
, et al.
소스
PLoS ONE, Vol 14, Iss 9, p e0222653 (2019)
PLoS ONE
Open Access (OpenAIRE)
Scopus
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