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1 . Academic Journal
Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen
저자
by
Eichenbaum, Gary
;
Yang, Kyunghee
;
Gebremichael, Yeshitila
;
Howell, Brett A.
;
Murray, F. Jay
, et al.
소스
In
Regulatory Toxicology and Pharmacology
December 2020 118
Full Text (ScienceDirect)
Scopus
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7 . Academic Journal
A critical review of the acetaminophen preclinical carcinogenicity and tumor promotion data and their implications for its carcinogenic hazard potential
저자
by
Murray, F. Jay
;
Monnot, Andrew D.
;
Jacobson-Kram, David
;
Cohen, Samuel M.
;
Hardisty, Jerry F.
, et al.
소스
In
Regulatory Toxicology and Pharmacology
December 2020 118
Full Text (ScienceDirect)
Scopus
Web of Science
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7 . Academic Journal
Prediction of Hepatic Efflux Transporter-Mediated Drug Interactions: When Is it Optimal to Measure Intracellular Unbound Fraction of Inhibitors?
저자
by
Guo, Cen
;
Yang, Kyunghee
;
Liao, Mingxiang
;
Xia, Cindy Q.
;
Brouwer, Kenneth R.
, et al.
소스
In
Journal of Pharmaceutical Sciences
September 2017 106(9):2401-2406
Full Text (ScienceDirect)
Scopus
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7 . Academic Journal
Quantitative Systems Toxicology Modeling Informed Safe Dose Selection of Emvododstat in Acute Myeloid Leukemia Patients.
저자
by
Yang, Kyunghee
;
Kong, Ronald
;
Spiegel, Robert
;
Baird, John D.
;
O'Keefe, Kylie
, et al.
소스
Clinical Pharmacology & Therapeutics; Mar2024, Vol. 115 Issue 3, p525-534, 10p
Scopus
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7 . Academic Journal
Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury
저자
by
Yang, Kyunghee
;
Guo, Cen
;
Woodhead, Jeffrey L.
;
St. Claire, Robert L., III
;
Watkins, Paul B.
, et al.
소스
In
Journal of Pharmaceutical Sciences
February 2016 105(2):443-459
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7 . Academic Journal
An updated review on drug-induced cholestasis: Mechanisms and investigation of physicochemical properties and pharmacokinetic parameters
저자
by
Yang, Kyunghee
;
Köck, Kathleen
;
Sedykh, Alexander
;
Tropsha, Alexander
;
Brouwer, Kim L.R.
.
소스
In
Journal of Pharmaceutical Sciences
September 2013 102(9):3037-3057
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7 . Academic Journal
The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury.
저자
by
Beaudoin, James J.
;
Clemens, Lara
;
Miedel, Mark T.
;
Gough, Albert
;
Zaidi, Fatima
, et al.
소스
International Journal of Molecular Sciences
. Jun2023, Vol. 24 Issue 11, p9692. 23p.
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7 . Academic Journal
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH).
저자
by
Murphy, William A.
;
Adiwidjaja, Jeffry
;
Sjöstedt, Noora
;
Yang, Kyunghee
;
Beaudoin, James J.
, et al.
소스
Clinical Pharmacology & Therapeutics; Feb2023, Vol. 113 Issue 2, p275-297, 23p
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7 . Academic Journal
Investigating bile acid-mediated cholestatic drug-induced liver injury using a mechanistic model of multidrug resistance protein 3 (MDR3) inhibition.
저자
by
Beaudoin, James J.
;
Yang, Kyunghee
;
Adiwidjaja, Jeffry
;
Taneja, Guncha
;
Watkins, Paul B.
, et al.
소스
Frontiers in Pharmacology; 1/17/2023, Vol. 14, p1-16, 16p, 2 Charts, 24 Graphs
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7 . Academic Journal
PS-052-End of study results from LIMT HDV study: 36% durable virologic response at 24 weeks post-treatment with pegylated interferon lambda monotherapy in patients with chronic hepatitis delta virus infection
저자
by
Etzion, Ohad
;
Hamid, Saeed Sadiq
;
Lurie, Yoav
;
Gane, Edward
;
Bader, Nimrah
, et al.
소스
In
Journal of Hepatology
April 2019 70(1) Supplement:e32-e32
Full Text (Clinical Key)
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