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1 . Academic Journal
Activity of the multitargeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL–positive leukemic cells
저자
by
Tanaka, Ruriko
;
Squires, Matthew S.
;
Kimura, Shinya
;
Yokota, Asumi
;
Nagao, Rina
, et al.
소스
In
Blood
23 September 2010 116(12):2089-2095
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7 . Academic Journal
AT9283, a Potent Inhibitor of JAK2, Is Active in JAK2 V617F Myeloproliferative Disease Models.
저자
by
Squires, Matthew S.
;
Curry, Jayne E.
;
Dawson, Mark A.
;
Scott, Mike A.
;
Barber, Kelly
, et al.
소스
In
Blood
16 November 2007 110(11):3537-3537
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7 . Academic Journal
AT7519, a Potent CDK Inhibitor, Is Active in Leukemia Models and Primary CLL Patient Samples.
저자
by
Squires, Matthew S.
;
Feltell, Ruth E.
;
Lock, Victoria
;
Smith, Donna M.
;
Lewis, Jon E.
, et al.
소스
In
Blood
16 November 2007 110(11):3127-3127
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7 . Academic Journal
AT9283, a potent inhibitor of the Aurora kinases and Jak2, has therapeutic potential in myeloproliferative disorders
저자
by
Dawson, Mark A.
;
Curry, Jayne E.
;
Barber, Kelly
;
Beer, Philip A.
;
Graham, Brent
, et al.
소스
British Journal of Haematology
. Jul 01, 2010 150(1):46-57
Full Text (Wiley)
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7 . Academic Journal
Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells
저자
by
Squires, Matthew S.
;
Hudson, E. Ann
;
Howells, Lynne
;
Sale, Stewart
;
Houghton, Catherine E.
, et al.
소스
Biochemical Pharmacology
. Feb2003, Vol. 65 Issue 3, p361. 16p.
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7 . Periodical
Cell-cycle arrest by PD184352 requires inhibition of extracellular signal-regulated kinases (ERK) 1/2 but not ERK5/BMK1
저자
by
SQUIRES, Matthew S.
;
NIXON, Paula M.
;
COOK, Simon J.
.
소스
Biochemical Journal; September 2002, Vol. 366 Issue: 2 p673-680, 8p
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5 . Academic Journal
AT7519, a Cyclin-Dependent Kinase Inhibitor, Exerts Its Effects by Transcriptional Inhibition in Leukemia Cell Lines and Patient Samples
저자
by
Squires, Matthew S.
;
Cooke, Laurence
;
Lock, Victoria
;
Qi, Wenqing
;
Lewis, E. Jonathan
, et al.
소스
MOLECULAR CANCER THERAPEUTICS
; APR 2010, 9 4, p920-p928, 9p.
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7 . Academic Journal
Biological characterization of AT7519, a small-molecule inhibitor of cyclin-dependent kinases, in human tumor cell lines
저자
by
Squires, Matthew S.
;
Feltell, Ruth E.
;
Wallis, Nicola G.
;
Lewis, E. Jonathan
;
Smith, Donna-Michelle
, et al.
소스
MOLECULAR CANCER THERAPEUTICS
; FEB 2009, 8 2, p324-p332, 9p.
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7 . Academic Journal
AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor with Potent Activity Against Aurora Kinase and STAT3 In Combination with Lenalidomide Results In Synergistic Anti-Myeloma Activity
저자
by
Santo, Loredana
;
Hideshima, Teru
;
Cirstea, Diana
;
Bandi, Madhavi L.
;
Nelson, Erik A.
, et al.
소스
BLOOD
; NOV 19 2010, 116 21, p1234-p1235, 2p.
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7 . Academic Journal
Outcome of Aurora Kinase Inhibition of Acute Myeloid Leukemia by AT9283 Is Dependent upon the Presence or Absence of Mutations in Type 1 Oncogenic Kinase Signalling Pathways
저자
by
Goodall, John
;
Squires, Matthew S.
;
Lock, Vicky
;
Ravandi, Farhad
;
Kantarjian, Hagop M.
, et al.
소스
BLOOD
; NOV 16 2008, 112 11, p570-p571, 2p.
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