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1 . Academic Journal
Antileukemic effects of the novel, mutant FLT3 inhibitor NVP-AST487: effects on PKC412-sensitive and -resistant FLT3-expressing cells
저자
by
Weisberg, Ellen
;
Roesel, Johannes
;
Bold, Guido
;
Furet, Pascal
;
Jiang, Jingrui
, et al.
소스
In
Blood
15 December 2008 112(13):5161-5170
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7 . Academic Journal
Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain
저자
by
Heidel, Florian
;
Solem, Fian K.
;
Breitenbuecher, Frank
;
Lipka, Daniel B.
;
Kasper, Stefan
, et al.
소스
In
Blood
1 January 2006 107(1):293-300
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7 . Academic Journal
Comparison of the Profile of the AML Drug Midostaurin (Rydapt®) As a Kinase Inhibitor with Those of Its Predominant Primary Human Metabolites
저자
by
Manley, Paul W
;
Caravatti, Giorgio
;
Furet, Pascal
;
Roesel, Johannes
;
Tran, Phi
, et al.
소스
In
Blood
8 December 2017 130 Supplement 1:1383-1383
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7 . Academic Journal
Comparison of the Kinase Profile of Midostaurin (Rydapt) with That of Its Predominant Metabolites and the Potential Relevance of Some Newly Identified Targets to Leukemia Therapy.
저자
by
Manley, Paul W.
;
Caravatti, Giorgio
;
Furet, Pascal
;
Roesel, Johannes
;
Tran, Phi
, et al.
소스
Biochemistry; 9/25/2018, Vol. 57 Issue 38, p5576-5590, 15p
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7 . Academic Journal
Novel β-lactam derivatives: Potent and selective inhibitors of the chymotrypsin-like activity of the human 20S proteasome
저자
by
Imbach, Patricia
;
Lang, Marc
;
García-Echeverría, Carlos
;
Guagnano, Vito
;
Noorani, Maria
, et al.
소스
In
Bioorganic & Medicinal Chemistry Letters
2007 17(2):358-362
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7 . Academic Journal
Investigation into CYP3A4-mediated drug-drug interactions on midostaurin in healthy volunteers.
저자
by
Dutreix, Catherine
;
Munarini, Florence
;
Lorenzo, Sebastien
;
Roesel, Johannes
;
Wang, Yanfeng
.
소스
Cancer Chemotherapy & Pharmacology
. Dec2013, Vol. 72 Issue 6, p1223-1234. 12p.
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7 . Academic Journal
PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder.
저자
by
Chen, Jing
;
Deangelo, Daniel J.
;
Kutok, Jeffery L.
;
Williams, Ifor R.
;
Lee, Benjamin H.
, et al.
소스
Proceedings of the National Academy of Sciences of the United States of America
. 10/5/2004, Vol. 101 Issue 40, p14479-14484. 6p.
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7 . Academic Journal
HIV-1 Protease Inhibitors: Development, Status, and Potential Role in the Treatment of AIDS HIV 1-Protease-Inhibitoren: Entwicklung, gegenwärtiger Stand und ihre mögliche Bedeutung in der AIDS-Behandlung.
저자
by
Lang, Marc
;
Roesel, Johannes
.
소스
Archiv der Pharmazie; 1993, Vol. 326 Issue 12, p921-924, 4p
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4 . Periodical
Antileukemic Effects of Novel First- and Second-Generation FLT3 Inhibitors: Structure-Affinity Comparison
저자
by
Weisberg, Ellen
;
Roesel, Johannes
;
Furet, Pascal
;
Bold, Guido
;
Imbach, Patricia
, et al.
소스
Genes & Cancer; October 2010, Vol. 1 Issue: 10 p1021-1032, 12p
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7 . Periodical
Uniform sensitivity of FLT3 activation loop mutants to the tyrosine kinase inhibitor midostaurin
저자
by
Barry, Elly V.
;
Clark, Jennifer J.
;
Cools, Jan
;
Roesel, Johannes
;
Gilliland, D. Gary
.
소스
Blood; December 2007, Vol. 110 Issue: 13 p4476-4479, 4p
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