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1 . Periodical
Signal peptide mimicry primes Sec61 for client-selective inhibition
저자
by
Rehan, Shahid
;
Tranter, Dale
;
Sharp, Phillip P.
;
Craven, Gregory B.
;
Lowe, Eric
, et al.
소스
Nature Chemical Biology; September 2023, Vol. 19 Issue: 9 p1054-1062, 9p
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7 . Academic Journal
Zetomipzomib (KZR-616) attenuates lupus in mice via modulation of innate and adaptive immune responses.
저자
by
Muchamuel, Tony
;
Fan, R. Andrea
;
Anderl, Janet L.
;
Bomba, Darrin J.
;
Johnson, Henry W. B.
, et al.
소스
Frontiers in Immunology; 3/10/2023, Vol. 14, p1-17, 17p
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7 . Periodical
Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
저자
by
Fang, Ying
;
Johnson, Henry
;
Anderl, Janet L.
;
Muchamuel, Tony
;
McMinn, Dustin
, et al.
소스
Drug Metabolism and Disposition; 2021, Vol. 49 Issue: 9 p810-821, 12p
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7 . Academic Journal
Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2S,3R)‑N‑((S)‑3-(Cyclopent-1-en-1-yl)-1-((R)‑...
저자
by
Johnson, Henry W. B.
;
Lowe, Eric
;
Anderl, Janet L.
;
Fan, Andrea
;
Muchamuel, Tony
, et al.
소스
Journal of Medicinal Chemistry; 12/27/2018, Vol. 61 Issue 24, p11127-11143, 17p
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7 . Academic Journal
Dose Intensive Administration of PR-047, a Novel Orally Bioavailable Inhibitor of the 20S Proteasome, Is Well Tolerated in Experimental Animals.
저자
by
Muchamuel, Tony
;
Kapur, Shirin
;
Kirk, Christopher J
;
Jiang, Jing
;
Lee, Susan
, et al.
소스
In
Blood
20 November 2009 114(22):4910-4910
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7 . Academic Journal
Preclinical Pharmacology and in Vitro Characterization of PR-047, An Oral Inhibitor of the 20S Proteasome
저자
by
Muchamuel, Tony
;
Aujay, Monette
;
Bennett, Mark K
;
Dajee, Maya
;
Demo, Susan
, et al.
소스
In
Blood
16 November 2008 112(11):3671-3671
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7 . Academic Journal
The Selective Proteasome Inhibitor Carfilzomib Is Well Tolerated in Experimental Animals with Dose Intensive Administration
저자
by
Kirk, Christopher J
;
Jiang, Jing
;
Muchamuel, Tony
;
Dajee, Maya
;
Swinarski, Deborah
, et al.
소스
In
Blood
16 November 2008 112(11):2765-2765
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7 . Academic Journal
Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis
저자
by
Basler, Michael
;
Mundt, Sarah
;
Muchamuel, Tony
;
Moll, Carlo
;
Jiang, Jing
, et al.
소스
Embo Molecular Medicine
. Feb 01, 2014 6(2):226-238
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7 . Academic Journal
Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2S,3R)-N-((S)-3-(Cyclopent-1-en-1-yl)-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-((S)-2-(2-morpholinoacetamido)propanamido)propenannide)
저자
by
Johnson, Henry W. B.
;
Lowe, Eric
;
Anderl, Janet L.
;
Fan, Andrea
;
Muchamuel, Tony
, et al.
소스
JOURNAL OF MEDICINAL CHEMISTRY
; DEC 27 2018, 61 24, p11127-p11143, 17p.
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7 . Academic Journal
Discovery and Early Clinical Development of Selective Immunoproteasome Inhibitors.
저자
by
Kirk, Christopher J.
;
Muchamuel, Tony
;
Wang, Jinhai
;
Fan, R. Andrea
.
소스
Cells (2073-4409)
. Jan2022, Vol. 11 Issue 1, p9. 1p.
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