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1 .
A Dual Inhibitor of DYRK1A and GSK3β for β‐Cell Proliferation: Aminopyrazine Derivative GNF4877
저자
by
Tingting Mo
;
Yefen Zou
;
Weijun Shen
;
Zhihong Huang
;
Xiaoyue Zhang
, et al.
소스
ChemMedChem
. 15:1562-1570
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7 .
Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133
저자
by
Bo Liu
;
Sukwon Ha
;
H. Michael Petrassi
;
Kate Jacobsen
;
George Harb
, et al.
소스
Journal of Medicinal Chemistry
. 63:2958-2973
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7 .
One-Pot Electrochemical Nickel-Catalyzed Decarboxylative Sp2–Sp3 Cross-Coupling
저자
by
Loren Jon
;
Ananda Herath
;
Andrew Valiere
;
Jim Yuchen Chang
;
Ashley Chong
, et al.
소스
Organic Letters
. 21:816-820
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7 .
Generation and Cross-Coupling of Organozinc Reagents in Flow
저자
by
Loren Jon
;
Valentina Molteni
;
Shifeng Pan
;
Ananda Herath
.
소스
Organic Letters
. 20:7429-7432
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6 .
Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension
저자
by
Andrew C. Pearce
;
Sylvie Chamoin
;
Matthew Thomas
;
Loren Jon
;
Deborah Haggart
, et al.
소스
Journal of Medicinal Chemistry
. 59:7901-7914
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7 .
(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors
저자
by
Nanxin Li
;
Loren Jon
;
Fangxian Sun
;
Van Phung
;
AnneMarie Culazzo
, et al.
소스
ACS Medicinal Chemistry Letters
. 6:562-567
Open Access (OpenAIRE)
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7 .
TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenografts
저자
by
Loren Jon
;
Valentina Molteni
;
Nanxin Li
;
W. Perry Gordon
;
Garrett M. Brodeur
, et al.
소스
Cancer Chemotherapy and Pharmacology
. 75:131-141
Full Text (Springer)
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7 .
Liver X receptor modulators: a review of recently patented compounds (2009 – 2012)
저자
by
Loren Jon
;
Zhihong Huang
;
Valentina Molteni
;
Bryan Laffitte
.
소스
Expert Opinion on Therapeutic Patents
. 23:1317-1335
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6 .
Discovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models
저자
by
Loren Jon
;
Yelena Sarkisova
;
Fangxian Sun
;
Yong Jia
;
Guoxun Liu
, et al.
소스
ACS medicinal chemistry letters
. 3(2)
Open Access (OpenAIRE)
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7 .
Synthesis of a D3-symmetric 'trefoil' knotted cyclophane
저자
by
Loren Jon
;
Karla I. Arias
;
Jay S. Siegel
;
Eli Zysman-Colman
;
Anthony Linden
, et al.
소스
Chemical Communications
. 47:9588
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