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1 .
Route Optimization of the Non-covalent Modulator of Hemoglobin PF-07059013 for the Treatment of Sickle Cell Disease, Part I: From Discovery Synthesis to First Kilogram-Scale Manufacture
저자
by
Aaron Baldwin
;
Shawn Cabral
;
Kris N. Jones
;
Jeffrey T. Kohrt
;
Chris Limberakis
, et al.
소스
Organic Process Research & Development
. 27:854-865
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7 .
Large-Scale Amidations in Process Chemistry: Practical Considerations for Reagent Selection and Reaction Execution
저자
by
Javier Magano
.
소스
Organic Process Research & Development
. 26:1562-1689
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3 .
Streamlined Synthesis of a Bicyclic Amine Moiety Using an Enzymatic Amidation and Identification of a Novel Solid Form
저자
by
Taegyo Lee
;
Richard A. Wisdom
;
Amber M. Johnson
;
Kevin M. Knopf
;
Giselle P. Reyes
, et al.
소스
Organic Process Research & Development
. 25:1419-1430
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7 .
Kinetic and Data-Driven Reaction Analysis for Pharmaceutical Process Development
저자
by
Ke Wang
;
Bryan Li
;
Jason Mustakis
;
Ruizhi Li
;
Javier Magano
, et al.
소스
Industrial & Engineering Chemistry Research
. 59:2409-2421
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7 .
Development of a Scalable Synthesis for an Inhaled pan-JAK Inhibitor
저자
by
Alexander Gontcharov
;
Peter Jones
;
Steven W. Kortum
;
David Pattavina
;
Seungwon Chung
, et al.
소스
Organic Process Research & Development
. 23:1990-2000
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7 .
Overcoming the Challenges of Making a Single Enantiomer N-1 Substituted Tetrazole Prodrug Using a Tin-Mediated Alkylation and Enzymatic Resolution
저자
by
Anne Akin
;
Asaad S. Nematalla
;
Kevin E. Henegar
;
Javier Magano
;
Thomas A. Brandt
, et al.
소스
Organic Process Research & Development
. 23:1167-1177
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7 .
The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future
저자
by
Andrew D. Campbell
;
Rubén Haro
;
Thomas Andrew Brandt
;
Melodie Christensen
;
David B. Damon
, et al.
소스
Organic Process Research & Development
. 23:1213-1242
Open Access (OpenAIRE)
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7 . Academic Journal
The Synthesis of a Dopamine D2Partial Agonist for the Treatment of Schizophrenia.
저자
by
Javier Magano
;
Alison Acciacca
;
Anne Akin
;
Benjamin M. Collman
;
Brian Conway
, et al.
소스
Organic Process Research & Development; May2009, Vol. 13 Issue 3, p555-566, 12p
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7 . Academic Journal
The Synthesis of (S)-5-Fluoro-1-(2-fluorophenyl)-3-(piperidin-3-ylmethoxy)-1H-indazole, a Norepinephrine/Serotonin Reuptake Inhibitor for the Treatment of Fibromyalgia.
저자
by
Javier Magano
;
Michael Waldo
;
Derek Greene
;
Eric Nord
.
소스
Organic Process Research & Development; Aug2008, Vol. 12 Issue 5, p877-883, 7p
Full Text (ACS)
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6 .
Palbociclib Commercial Manufacturing Process Development. Part II: Regioselective Heck Coupling with Polymorph Control for Processability
저자
by
Javier Magano
;
Nathan D. Ide
;
David R. Bill
;
Marie O’Brien
;
Kyle R. Leeman
, et al.
소스
Organic Process Research & Development
. 20:1203-1216
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