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1 . Academic Journal
Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes.
저자
by
Xiang Wang
;
Bondar, Vitaliy V.
;
Davis, Oliver B.
;
Maloney, Michael T.
;
Agam, Maayan
, et al.
소스
eLife
. 12/8/2023, p1-24. 24p.
Web of Science
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7 . Academic Journal
A Fixable Fluorescence‐Quenched Substrate for Quantitation of Lysosomal Glucocerebrosidase Activity in Both Live and Fixed Cells.
저자
by
Zhu, Sha
;
Deen, Matthew C.
;
Zhu, Yanping
;
Gilormini, Pierre‐André
;
Chen, Xi
, et al.
소스
Angewandte Chemie
. 10/2/2023, Vol. 135 Issue 40, p1-11. 11p.
Full Text (Wiley)
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7 . Academic Journal
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
저자
by
Logan, Todd
;
Simon, Matthew J.
;
Rana, Anil
;
Cherf, Gerald M.
;
Srivastava, Ankita
, et al.
소스
In
Cell
14 March 2024 187(6):1565-1566
Full Text (ScienceDirect)
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7 . Academic Journal
LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease.
저자
by
Jennings, Danna
;
Huntwork‐Rodriguez, Sarah
;
Vissers, Maurits F.J.M.
;
Daryani, Vinay M.
;
Diaz, Dolores
, et al.
소스
Movement Disorders
. Mar2023, Vol. 38 Issue 3, p386-398. 13p.
Full Text (Wiley)
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7 . Academic Journal
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson's disease.
저자
by
Jennings, Danna
;
Huntwork-Rodriguez, Sarah
;
Henry, Anastasia G.
;
Sasaki, Jennifer C.
;
Meisner, René
, et al.
소스
Science Translational Medicine; 6/8/2022, Vol. 14 Issue 648, p1-17, 17p
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7 . Academic Journal
Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10.
저자
by
Wang, Xiang
;
Negrou, Elvira
;
Maloney, Michael T.
;
Bondar, Vitaliy V.
;
Andrews, Shan V.
, et al.
소스
Scientific Reports
. 6/18/2021, Vol. 11 Issue 1, p1-17. 17p.
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7 . Academic Journal
LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits.
저자
by
Baptista, Marco A. S.
;
Merchant, Kalpana
;
Barrett, Ted
;
Bhargava, Sakshi
;
Bryce, Dianne K.
, et al.
소스
Science Translational Medicine; 4/22/2020, Vol. 12 Issue 540, p1-14, 14p
Web of Science
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7 . Academic Journal
High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II
저자
by
Wang, Junhua
;
Bhalla, Akhil
;
Ullman, Julie C.
;
Fang, Meng
;
Ravi, Ritesh
, et al.
소스
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
; AUG 2020, 21 15, p5449 17p.
Scopus
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7 . Academic Journal
Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression
저자
by
Henry, Anastasia G.
;
Aghamohammadzadeh, Soheil
;
Samaroo, Harry
;
Chen, Yi
;
Mou, Kewa
, et al.
소스
Human Molecular Genetics
. Nov 01, 2015 24(21):6013-6028
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Full Text (OUP Near Archive)
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7 . Academic Journal
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice
저자
by
Ullman, Julie C.
;
Arguello, Annie
;
Getz, Jennifer A.
;
Bhalla, Akhil
;
Mahon, Cathal S.
, et al.
소스
SCIENCE TRANSLATIONAL MEDICINE
; MAY 27 2020, 12 545, peaay1163 13p.
Scopus
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