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1 . Academic Journal
Pharmacological characterization of SAGE‐718, a novel positive allosteric modulator of N‐methyl‐d‐aspartate receptors.
저자
by
Beckley, Jacob T.
;
Aman, Teresa K.
;
Ackley, Michael A.
;
Kazdoba, Tatiana M.
;
Lewis, Michael C.
, et al.
소스
British Journal of Pharmacology
. Apr2024, Vol. 181 Issue 7, p1028-1050. 23p.
Full Text (Wiley)
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7 . Academic Journal
Anticonvulsant profile of the neuroactive steroid, SGE-516, in animal models
저자
by
Hammond, Rebecca S.
;
Althaus, Alison L.
;
Ackley, Michael A.
;
Maciag, Carla
;
Martinez Botella, Gabriel
, et al.
소스
In
Epilepsy Research
August 2017 134:16-25
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7 . Academic Journal
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions.
저자
by
Tang, Weiting
;
Beckley, Jacob T.
;
Zhang, Jin
;
Song, Rui
;
Xu, Yuchen
, et al.
소스
Cellular & Molecular Life Sciences
. Feb2023, Vol. 80 Issue 2, p1-20. 20p.
Web of Science
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7 . Academic Journal
SAGE-718: A First-in-Class N‑Methyl‑d‑Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment.
저자
by
Hill, Matthew D.
;
Blanco, Maria-Jesus
;
Salituro, Francesco G.
;
Bai, Zhu
;
Beckley, Jacob T.
, et al.
소스
Journal of Medicinal Chemistry; 7/14/2022, Vol. 65 Issue 13, p9063-9075, 13p
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7 . Academic Journal
Preventing Phosphorylation of the GABA
A
R β3 Subunit Compromises the Behavioral Effects of Neuroactive Steroids.
저자
by
Vien, Thuy N.
;
Ackley, Michael A.
;
Doherty, James J.
;
Moss, Stephen J.
;
Davies, Paul A.
.
소스
Frontiers in Molecular Neuroscience; 3/31/2022, Vol. 15, p1-10, 9p
Web of Science
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7 . Academic Journal
Neuroactive Steroid N‑Methyl‑d‑aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological Activity.
저자
by
La, Daniel S.
;
Salituro, Francesco G.
;
Martinez Botella, Gabriel
;
Griffin, Andrew M.
;
Bai, Zhu
, et al.
소스
Journal of Medicinal Chemistry; 8/22/2019, Vol. 62 Issue 16, p7526-7542, 17p
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7 . Academic Journal
Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABA
A
receptors.
저자
by
Parakala, Manasa L.
;
Yihui Zhang
;
Modgil, Amit
;
Chadchankar, Jayashree
;
Thuy N. Vien
, et al.
소스
Journal of Biological Chemistry
. 8/9/2019, Vol. 294 Issue 32, p12220-12230. 11p.
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7 . Academic Journal
Neuroactive Steroids Reverse Tonic Inhibitory Deficits in Fragile X Syndrome Mouse Model.
저자
by
Modgil, Amit
;
Vien, Thuy N.
;
Ackley, Michael A.
;
Doherty, James J.
;
Moss, Stephen J.
, et al.
소스
Frontiers in Molecular Neuroscience; 2/5/2019, pN.PAG-N.PAG, 11p
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7 . Academic Journal
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1′-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)
A
Receptor
저자
by
Botella, Gabriel Martinez
;
Salituro, Francesco G.
;
Harrison, Boyd L.
;
Beresis, Richard T.
;
Bai, Zhu
, et al.
소스
Journal of Medicinal Chemistry
. Sep2017, Vol. 60 Issue 18, p7810-7819. 10p.
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7 . Academic Journal
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1′-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric...
저자
by
Botella, Gabriel Martinez
;
Salituro, Francesco G.
;
Harrison, Boyd L.
;
Beresis, Richard T.
;
Bai, Zhu
, et al.
소스
Journal of Medicinal Chemistry; Sep2017, Vol. 60 Issue 18, p7810-7819, 10p
Full Text (ACS)
Web of Science
Scopus
JCR 저널정보
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