Shooting the messenger: the neurobiology of depression.
- Resource Type
- Academic Journal
- Authors
- McCrae, Niall; Khan, Ehsan
- Source
- British Journal of Neuroscience Nursing (BR J NEUROSCI NURS), Aug/Sept2014; 10(4): 185-190. (6p)
- Subject
- Language
- English
- ISSN
- 1747-0307
Depression is a very common disorder with both psychological and biological manifestations. The prevailing rationale for antidepressant drug treatment is the serotonin hypothesis, but this is no longer accepted as an adequate explanation for depressive disorder. The role of other neurotransmitters such as glutamate may be important, but there is much to be learned. This review considers current evidence for neurophysiological factors in depression, and implications for care and treatment.