Background: Although the respiratory rate (RR) is a sensitive predictor of patient deterioration, it is often neglected. Moreover, only a few studies have investigated the factors that cause health professionals to disregard RR. Aims: This cross-sectional study aimed to elucidate the factors affecting the frequency of RR measurement by the nurses.Methods: An original questionnaire, comprising 18 factors extracted from previous studies, was administered to nurses from nine hospitals. Findings: Of the 644 eligible nurses, 592 (92%) completed the questionnaire. The adjusted odds ratios and 95% confidence intervals of the factors of importance, educational experiences, shortened-count method use, negative experiences, and inconvenience were 2.24 (1.13–4.45), 2.26 (1.20–4.26), 0.61 (0.42– 0.91), 0.45 (0.29–0.70), and 0.41 (0.26–0.65), respectively. Conclusion: Education, feedback systems, and automation are the primary issues that need attention. Prioritising these factors could provide a practical guide for optimising the frequency of RR measurement.