This chapter examines practical issues regarding Virtual Exchanges (VEs) for educational purposes in the university context and covers language use, cultural differences, time management, teacher collaboration, technology-related issues, assessment, and context specific factors. It charts the establishment of three academic collaborations between a university in Kyoto, Japan, and institutions in Asia, Africa, and Europe. The first collaboration follows a new hybrid model created at the Japanese university described here. In the Teaching Online Together (TOT) model, teachers in the Philippines interact with students in a tutorial style system to improve the students' English presentation skills via video conferencing. The second project, with a university in Kenya, is modelled on the intercultural telecollaboration or Cultura-type exchange approach (O'Dowd, 2018). Students from the respective institutions work together asynchronously to complete tasks related to the development of intercultural understanding and sensitivity. The third collaboration, with a university in Belgium, follows a shared syllabus approach (O'Dowd, 2018) in which teachers create course materials for students who then work together both synchronously and asynchronously to achieve their goals. [For the complete volume, "Virtual Exchange in the Asia Pacific: Research and Practice," see ED610332.]