Discovery of N-(3-Fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine (GSK962040), the First Small Molecule Motilin Receptor Agonist Clinical Candidate
Resource Type
Journal
Authors
Westaway, Susan M. ; Brown, Samantha L. ; Fell, Stephen C. M. ; Johnson, Christopher N. ; MacPherson, David T. ; Mitchell, Darren J. ; Myatt, James W. ; Stanway, Steven J. ; Seal, Jon T. ; Stemp, Geoffrey ; Thompson, Mervyn ; Lawless, Kirk ; McKay, Fiona ; Muir, Alison I. ; Barford, Jonathan M. ; Cluff, Chermaine ; Mahmood, Sadhia R. ; Matthews, Kim L. ; Mohamed, Shiyam ; Smith, Beverley ; Stevens, Alexander J. ; Bolton, Victoria J. ; Jarvie, Emma M. ; Sanger, Gareth J.
Source
JOURNAL OF MEDICINAL CHEMISTRY ; FEB 26 2009, 52 4, p1180-p1189, 10p.
Subject
Language
English
ISSN
00222623