Taking the temperature of lung cancer antigens
- Resource Type
- Brief Communication
- Authors
- Stewart, Paul A.; Jaeger, Alex M.
- Source
- Nature Cancer. 4(5):586-587
- Subject
- Language
- English
- ISSN
- 2662-1347
Antigen presentation is fundamental to anti-tumor immunity, but our understanding of the physiological and molecular inputs to the process in different contexts remains limited. Two new studies explore the contribution of cell-intrinsic proteolytic mechanisms and cell-extrinsic hot and cold tumor microenvironments in shaping the antigenic landscape in lung cancer.