Is the outcome of schizophrenia really better in developing countries?
- Resource Type
- article
- Authors
- Patel, Vikram; Cohen, Alex; Thara, Rangaswamy; Gureje, Oye
- Source
- Brazilian Journal of Psychiatry. June 2006 28(2)
- Subject
- Schizophrenia
Cross-cultural comparison
Developing countries
Human rights abuses
Prognosis
- Language
- English
- ISSN
- 1516-4446
That schizophrenia has a better prognosis in non-industrialized societies has become an axiom in international psychiatry; the evidence most often cited comes from three World Health Organization (WHO) cross-national studies. Although a host of socio-cultural factors have been considered as contributing to variation in the course of schizophrenia in different settings, we have little evidence from low-income countries that clearly demonstrates the beneficial influence of these variables. In this article, we suggest that the finding of better outcomes in developing countries needs re-examination for five reasons: methodological limitations of the World Health Organization studies; the lack of evidence on the specific socio-cultural factors which apparently contribute to the better outcomes; increasing anecdotal evidence describing the abuse of basic human rights of people with schizophrenia in developing countries; new evidence from cohorts in developing countries depicting a much gloomier picture than originally believed; and, rapid social and economic changes are undermining family care systems for people with schizophrenia in developing countries. We argue that the study of the long-term course of this mental disorder in developing countries is a major research question and believe it is time to thoroughly and systematically explore cross-cultural variation in the course and outcome of schizophrenia.