Alternatively spliced isoform of phosphodiesterase 4B (PDE4B)
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The present invention features nucleic acids and polypeptides encoding novel splice variant isoform of phosphodiesterase 4B (PDE4B). The polynucleotide sequence of PDE4Bsv1 is provided by SEQ ID NO: 3. The amino acid sequence of PDE4Bsv1 is provided by SEQ ID NO: 4. The present invention also provides methods for using PDE4B polynucleotides and proteins to screen for compounds that bind to PDE4B.