Pregnancy following oocyte donation in a woman with Noonanʼs syndrome and a balanced Robertsonian translocation a case report
- Resource Type
- Academic Journal
- Authors
- Engemise, Samuel; Croucher, Carolyn
- Source
- Archives of Gynecology and Obstetrics. Aug 01, 2007 276(2):185-187
- Subject
- Language
- English
- ISSN
- 0932-0067
Successful pregnancy in Noonanʼs syndrome and balanced Robertsonian translocation women is extremely rare. This is because pregnancies in these women usually end in spontaneous miscarriage or termination before 24 weeks gestation due to severe congenital anomaly. In this article, we report the case of a 41-years-old woman with Noonanʼs syndrome and balanced Robertsonian translocation. She was delivered by an elective caesarean section at 38 weeks of a live male infant following a second attempt of in vitro fertilisation (IVF) and embryo transfer from donor oocytes. The use of donor eggs and IVF in these women means more of them will achieve successful term pregnancy as in this case. It is therefore important that Obstetricians understand this rare condition and optimise care. This case highlights some of the medical problems encountered by Obstetricians in managing patients in this high risk group.