Individuals with intellectual and developmental disabilities (IDD) comprise a large proportion of neurologic clinic patients. Their myriad diagnoses include cerebral palsy, Down syndrome, and Autism Spectrum Disorder, with many of these disorders co-morbid with each other. Their abilities range from complete functional independence to complete functional dependence with variable requirements at baseline for life-sustaining supports, for example, home ventilators, gastrostomy tubes, or personal care assistants (PCAs). Often, simple viral illnesses can throw individuals with IDD into medical crisis which can include exacerbation of baseline challenges with muscle tone to inability to tolerate feeding to behavioral dysregulation that puts themselves or others at risk. As such, though we all feel vulnerable during the COVID-19 pandemic, our patients with IDD are particularly at risk.