Myocardial perfusion imaging (MPI) with single photon emission computed tomography (SPECT) is generally used to evaluate myocardial ischemia in patients with known or suspected coronary artery disease. Cardiac CT, on the other hand, enables non-invasive visualization of the coronary vessels. Myocardial bridging (MB) is a congenital anomaly characterized by an intramyocardial route of a coronary artery. It is commonly considered benign and rarely requires further evaluation or intervention. However, its clinical complications can be hazardous. We report a patient whose SPECT MPI study demonstrated a mild reversible perfusion defect at the apical anterior segment of the left ventricle that was later attributed to MB visualized on cardiac CT.