Lipomas of the retropharyngeal space are rare, and they do not cause symptoms until they reach a large size. Although retropharyngeal lipoma is an uncommon entity, several reports have appeared about it in the literature, where the treatment has routinely been surgical excision. We present a case of huge lipoma of the retropharyngeal space. It extended from the oropharynx to the inferior portion of thyroid gland, causing symptoms of globus and dysphagia in a 74-year-old male. The patient had multiple medical problems and had been on anticoagulants, so we approached the mass via transcervical incision. After a complete surgical resection, all the symptoms of the patient improved. A large retropharyngeal lipoma could also be differentially diagnosed as a laryngopharyngeal mass presenting symptoms of globus and dysphagia.