Objective: General To assess the prevalence of diabetes and quality of life among sample Specific · To determine the knowledge of diabetic complications among patient · To find out the physical, social and environmental domain of quality of life among patient. Methods: It is a cross-sectional study conducted among 200 patients visiting Global Hospital, Gwarko, Lalitpur, Nepal. Data were documented using a pre-tested questionnaire along with physical measurements (Weight, height, waist circumference and blood pressure) and blood samples were collected from the respective patients. BMI was calculated by the standard formula. In addition, structured survey was used to obtain information such as socio-demographic and knowledge on complications of diabetes. Collected records were accomplished for proper investigation and assessment. Results: In this study, prevalence of diabetes was 12% males and 14% females. 28.07% males and 24.61 % females were 45 years and above who reported history of diabetes. Individuals with waist circumference > 90 cm in males and >80 cm in females had a risk of diabetes in comparison with individuals with normal waist circumference. Comprehensive assessment of level of knowledge on the complications showed that majority (60.0 %) of type 2 diabetes patients did not have knowledge on diabetes complications, (26.9 %) had inadequate knowledge on diabetics complication while (18.1 %) had adequate knowledge. Among type 2 diabetes participants, 74% of those who were aware received treatment, and 31% of the treated subjects had their diabetes under control. 26.1 % of the participants reported smoking regularly. No association was found between smoking and the prevalence of diabetes. Conclusion: Further expansion of diabetic educative programs, confession on this information may contribute to more focus on early diagnosis and treatment of disease which can improve self-regulatory awareness of complications which may reduce the morbidity and mortality.