In this paper, the mechanical characteristics of the open type hyperbolic-parabolic membrane structure under wind load were investigated. First, the numerical simulation of a typical plane membrane structure was performed based on the Large-Eddy Simulation method. The accuracy of the simulation method was validated by the corresponding wind tunnel test results. Then, the wind load shape coefficients of open type hyperbolic-parabolic membrane structures are obtained from the series of numerical calculations and compared with the recommended values in the “Technical Specification for Membrane Structures (CECS 158: 2015). Finally, the influences of the wind directions and wind speeds on the mean wind pressure distribution of open type hyperbolic-parabolic membrane structures were investigated. This study aims to gain a better understanding of the wind-induced response for this type of structure and be useful to engineers and researchers.