Higher coating rate and larger enthalpy value of phase change materials (PCMs) are the key content oftemperature-regulated textile. The warming impact of traditional temperature-regulated textiles, namely no microencapsulatedphase change materials (MPCMs) loading, is impermanent. In this paper, a high-efficiency heat storage and thermo-regulatedMPCMs based on butyl stearate (BS)/hexadecanol (HD) binary system was synthesized successfully. It is found that theMPCMs take on spherical shape, as well as relatively uniform particle size. The mean particle size of MPCMs with smoothand compact surface is 1.755 um. Moreover, the phase change temperature of the MPCMs varied from 21.06 °C to 27.33 °C,and the latent heat of MPCMs was up to 73.78 J/g. A new type of intelligent textile material, namely temperature-regulatedseaweed fibers were obtained by using wet spinning process adopting the resulted MPCMs. As a result, the MPCMs endowsthe seaweed fibers good temperature-regulated property.