Researches on MenSCs have been mature in its separation and cultivation techniques, differentiation potential and characteristics, and won't be repeated in this article. As scientists began to explore more possible clinical applications of MenSCs, their prospects have been testified in an ever increasing number of disease cases. The transplant of MenSCs and its differentiated products as the most common practice has been proved effective to treat lung injury and cancer, acute liver injury, liver fibrosis, peripheral nerve injury and neuroglioma. In the treatment of gynecological diseases, MenSCs transplant offers a novel and effective therapy for premature ovarian failure and intrauterine adhesion helpless by normal drug and surgeries. In recent years, targeted therapy using adenovirus infected MenSCs as vehicle gene is gaining wide attention. In its treatment of neurogliocytoma and gynecological oncology, its capacity to get round human immune barrier and precisely target oncology cells is worthy of further exploration.