N-Acetylcysteine’s Renoprotective Effect in Cardiac Surgery: A Systematic Review and Meta-Analysis
- Resource Type
- Journal Article
- Authors
- Giap Swee Kang; HaiDong Luo; Kristine LK Teoh; Theo Kofidis; Ying Kiat Tan
- Source
- Annals of Thoracic and Cardiovascular Surgery. 2022, 28(2):138
- Subject
- N-acetylcysteine
acute kidney injury
cardiac surgery
- Language
- English
- ISSN
- 1341-1098
2186-1005
Results: Overall meta-analytic estimates of all 10 included trials showed that NAC did not have a significant effect (odds ratio [OR]: 0.84, 95% confidence interval [CI]: 0.64–1.10) on AKI. Further subgroup analysis did not show a significant benefit of NAC in preventing AKI.