Catheter fractures are a rare complication of totally implantable venous access ports (TIVAPs); however, to the best of our knowledge, no study has reported fractured TIVAP central venous catheters (CVC) causing cardiac perforation or cardiac tamponade. An 82-year-old man presented to the emergency complaining of chest pain. With a history of advanced gastric cancer, the patient had undergone surgical treatment and TIVAP implantation thorough the right internal jugular vein four years ago. Chest radiography revealed that the CVC was fractured at the neck and had caused cardiac perforation and tamponade. An emergency operation confirmed that the perforation site was located on the right ventricle and that the fractured CVC was in the pericardium. The perforation site was sutured and repaired. Previous studies have explored the cause of CVC rupture. We suspected that in our case, the CVC fracture was caused by (1) a large distance between the clavicle and CVC flexion point; (2) a narrow CVC flexion angle; or (3) the CVC’s material-silicon. Interventional radiology helps remove fractured CVCs. In our case, cardiac surgery and suture repair were performed for cardiac perforation and tamponade.