A 53-year-old man received interferon therapy for hepatitis C at the age of 30, but the treatment failed. At the age of 50, he was initiated direct-acting antivirals (DAA) treatment after confirming the absence of any hepatic masses, and the serum HCV-RNA disappeared. Subsequently, the patient was checked by abdominal ultrasonography every 3 months, and a year and 7 months after sustained viral response was achieved, a 15-mm hepatic mass was detected in the lateral segment of the liver. The tumor was stained in the early phase on sonazoid-enhanced ultrasonography, showing hypoperfusion in the Kupffer phase. We made a preoperative diagnosis of hepatocellular carcinoma, and laparoscopic lateral sectionectomy of the liver was performed. On histopathological examination, the tumor was diagnosed as an intrahepatic cholangiocarcinoma. The postoperative course was uneventful, and the patient was discharged 10 days after the operation. At present, one year after the operation, the patient remains alive without recurrence.