The study aimed to compare serum zinc levels between children with neurodevelopmental disorders and healthy children. A total of 63 school-aged children (49 boys and 14 girls) with neurodevelopmental disorders were included in the patients group, and in the previous study, 380 healthy age-matched children constituted the control group. Zinc deficiency was found in 19 children (30%), latent zinc deficiency in 39 (62%), and five patients (8%) had normal zinc levels. Serum zinc level in children with neurodevelopmental disorders was significantly lower than the control data for the healthy group (p<0.001). Most children with neurodevelopmental disorders had either attention-deficit/hyperactivity disorder (36 patients, 54%) and autism spectrum disorder (22 patients, 39%). There was no significant difference seen in the diseases (p=0.32) and sex (p=0.95). Children with neurodevelopmental disorders tend to have a zinc deficiency. No significant serum zinc level differences were notes based on disease or sex.