The Asian Society for Clinical Pathology and Laboratory Medicine (ASCPaLM) is a non-profit organization that was founded in 1975 for the societies primarily engaged in laboratory medicine (clinical pathology). Its aim is to enhance the development and practice of laboratory medicine to promote better support the health and well-being of the communities it serves. The organization support its constituent societies in Asia, as well as its other members through communication, cooperation in education, research and practice. The Japanese Society for Laboratory Medicine (JSLM) has played a crucial role in establishing ASCPaLM and continues to be actively involved in its operation. It needs to keep to demonstrate leadership in these activities, leveraging its innovation initiative, particularly through collaboration with industry sectors. The ASCPaLM contributed to combatting the COVID-19 pandemic by sharing experiences and knowledge, with clinical pathologists and laboratory professionals at the forefront of laboratory practice and services. To address the weakness of communities that the pandemic has exposed, it is an important time to take action and achieve the the Sustainable Development Goals (SDGs), by promoting innovation, technology transfer, and continuous quality improvement of the laboratory practice to meet requirements in international standards.